{"product_id":"prohealth-nmnr™-pro-synergy-90-capsules","title":"ProHealth NMNR™ Pro Synergy - 90 capsules","description":"\u003cp\u003e\u003cstrong\u003eFinally, NMN and NR Together\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNMN and NR elevate NAD+ through complementary pathways*\u003csup\u003e1,2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ePowers cellular energy to support brain, heart, and whole-body vitality*\u003csup\u003e3-5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eEnhances mitochondrial performance and resilience with age*\u003csup\u003e3-5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eIncludes TMG to support balanced methylation*\u003csup\u003e6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eAddresses key drivers of healthy aging*\u003csup\u003e2,7\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eThe Next Evolution in NAD+ Science\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNMNR™ Pro Synergy unites NMN and NR in one advanced formula designed to restore and sustain cellular NAD+ levels. This dual-precursor approach fuels energy production, supports DNA repair, and promotes cellular revitalization. With added TMG to maintain methylation balance, the formula delivers comprehensive, long-term support for healthy aging and vitality.*\u003csup\u003e1-7\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow It Works\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis formula is designed to help restore NAD+ through three complementary mechanisms.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNMN (Nicotinamide Mononucleotide)\u003c\/strong\u003e\u003cbr\u003eNMN is an immediate precursor to NAD+ that bypasses early rate-limiting steps in the salvage pathway. It supports rapid increases in intracellular NAD+, helping energize mitochondria and activate sirtuin enzymes involved in cellular repair and longevity.*\u003csup\u003e3,4\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNR (Nicotinamide Riboside)\u003c\/strong\u003e\u003cbr\u003eNR complements NMN by supporting systemic NAD+ synthesis through distinct transport and conversion pathways. Hydrogen malate enhances NR bioavailability and provides malic acid, a key component of the Krebs energy cycle.*\u003csup\u003e2,8\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrimethylglycine (TMG)\u003c\/strong\u003e\u003cbr\u003eTMG provides methyl groups needed to recycle homocysteine into methionine, supporting balanced methylation and maintaining NAD+ homeostasis. It also protects against the potential depletion of methyl donors during NAD+ synthesis from NMN and NR.*\u003csup\u003e6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTogether, these clinically studied ingredients help restore healthy NAD+ levels and strengthen the body’s natural capacity for energy, repair, and resilience.*\u003csup\u003e1-5\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy NAD+ Matters\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNicotinamide Adenine Dinucleotide (NAD) is a vital coenzyme present in every cell, essential for creating and maintaining energy throughout the body. Each human cell contains hundreds of millions of NAD+ molecules that power metabolism, drive DNA repair, and activate key enzymes like PARPs and sirtuins, which sustain cellular integrity, stress resilience, and healthy aging.\u003csup\u003e9,10\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eAs we age, NAD+ levels naturally decline. This reduction diminishes mitochondrial energy production and weakens the activity of sirtuins, PARPs, and AMPK, leaving cells more susceptible to damage. The decline is further accelerated by increased CD38 activity — an enzyme that degrades NAD+ and disrupts energy balance.\u003csup\u003e9,10\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eRestoring NAD+ levels with precursors such as NMN and NR, complemented by TMG for methylation support, helps sustain cellular energy production and preserve healthy NAD+ metabolism over time.*\u003csup\u003e6,9,10\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDual-Pathway NAD+ Support:\u003c\/strong\u003e Combines NMN and NR to enhance both intracellular and systemic NAD+ synthesis.*\u003csup\u003e1,2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylation-Enhanced:\u003c\/strong\u003e Includes 300 mg TMG per serving to maintain methylation balance and support healthy clearance of NAD+ metabolites.*\u003csup\u003e6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargeted Liver Support:\u003c\/strong\u003e Supplies key nutrients that drive hepatic detoxification and help restore balance.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Supported Dosing:\u003c\/strong\u003e Delivers 1000 mg of NAD+ precursors per serving, reflecting levels used in human studies demonstrating improvements in cellular and metabolic function.*\u003csup\u003e3-5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergistic Design:\u003c\/strong\u003e Developed to activate multiple longevity mechanisms — from NAD+ synthesis and recycling to sirtuin and AMPK activation.*\u003csup\u003e10\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eThe ProHealth Difference\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Verified three times by independent labs for purity and potency.\u003c\/li\u003e\n\u003cli\u003e \u003cstrong\u003eFull Transparency:\u003c\/strong\u003e Third-party test results published online for complete confidence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufactured:\u003c\/strong\u003e Proudly manufactured in the USA in FDA-registered, GMP-certified facilities since 1988.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e If you’re not fully satisfied, we’ll refund your purchase in full.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eA Word from our Chief Science Officer\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\"People tend to fall into camp NMN or camp NR. But why not do both? These two forms of vitamin B3 act at different points in the NAD+ pathway, working together to sustain NAD+ levels across multiple tissues. Used in combination, they provide broader support for the entire NAD+ metabolome.\"\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient Info\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNicotinamide Mononucleotide (NMN):\u003c\/strong\u003e A vitamin B3 derivative and essential precursor in the NAD+ production pathway.*\u003cbr\u003e\u003cstrong\u003eNicotinamide Riboside (NR):\u003c\/strong\u003e A vitamin B3 derivative and essential precursor in the NAD+ production pathway.*\u003cbr\u003e\u003cstrong\u003eTrimethylglycine (TMG):\u003c\/strong\u003e A natural methyl donor that supports NAD+ metabolism and maintains homocysteine balance.*\u003c\/p\u003e","brand":"ProHealth","offers":[{"title":"Default Title","offer_id":54297195479323,"sku":"PH660","price":35.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0966\/4485\/8139\/files\/PH660_FRNT_250CC_600x600-REV0925_2x_9d72b91f-d010-4dc6-b4b9-fe420c83a084.webp?v=1792410255","url":"https:\/\/shop.hasanmirzamd.com\/products\/prohealth-nmnr%e2%84%a2-pro-synergy-90-capsules","provider":"Hasan Mirza, MD","version":"1.0","type":"link"}