{"product_id":"prohealth-pure-fisetin-250-mg-60-capsules","title":"ProHealth Pure Fisetin - 250 mg, 60 capsules","description":"\u003cp\u003e\u003cstrong\u003eThe Ultimate Weapon Against Zombie Cells\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePowerful 5-day cellular reset*\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eClear out “zombie” senescent cells*\u003csup\u003e1-2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eRestore and revitalize tissues*\u003csup\u003e1-3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eUnlock youthful aging from within*\u003csup\u003e1-4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWhy Fisetin?\u003cbr\u003e\u003c\/strong\u003eFisetin is a powerful plant flavonoid that supports the body's natural ability to eliminate senescent cells—old dysfunctional cells that accumulate with age and contribute to age-related decline. Groundbreaking research reveals fisetin’s ability to promote deep cellular renewal, supporting full-body rejuvenation and long-term vitality.*\u003csup\u003e1-5\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUltra-Pure Extract:\u003c\/strong\u003e Sourced from the stems of the Japanese fruit wax tree (\u003cem\u003eRhus succedanea\u003c\/em\u003e) for exceptional purity and potency.\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotent Senolytic:\u003c\/strong\u003e One of the most effective compounds for eliminating senescent cells, a key driver of aging.*\u003csup\u003e1-5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e Multiple Longevity Benefits:\u003c\/strong\u003e Supports antioxidant defenses, activates autophagy and SIRT1, and helps manage SASP factors—compounds released by senescent cells that can spread cellular dysfunction.*\u003csup\u003e5-9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtra Strength Formula:\u003c\/strong\u003e 1,500 mg \"Senolytic Dose\"*\u003csup\u003e3\u003c\/sup\u003e \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShort-Term Protocol:\u003c\/strong\u003e ODesigned by doctors to mimic the most effective senolytic protocols studied in research.*\u003csup\u003e1,3\u003c\/sup\u003e  \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Subjected to three rounds of independent third-party lab testing to ensure unmatched potency and purity.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Transparency:\u003c\/strong\u003e In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufactured in the USA:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities, adhering to the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We’re confident you’ll love our product. If you’re not satisfied, contact our Santa Barbara, CA office for a full refund within 100 days—no hassle, no questions asked.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFisetin is a naturally occurring flavonoid known for its distinctive yellow color. Its name comes from the German word “fisetholz,” referring to a traditional yellow dye. In plants, fisetin plays a key role in defending against environmental stressors like UV radiation and pathogens.\u003cbr\u003e\u003cbr\u003eBeyond its role in plants, fisetin has gained considerable scientific interest for its potential to support human health. It is now recognized as one of the most promising senolytic compounds for healthy aging. A groundbreaking 2018 study identified fisetin as the most potent senolytic agent among 10 flavonoid polyphenols, including quercetin, resveratrol, curcumin, and apigenin. The study demonstrated that fisetin effectively reduced senescent cell markers in vitro while restoring youthful tissue function in vivo.*\u003csup\u003e2\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003eEarly research on fisetin as a senolytic involved high doses of around 100 mg per kg of body weight—equating to approximately 6,800 mg for an average adult. However, more recent studies indicate that much lower doses of around 20 mg per kg (about 1,400 mg for an average adult) are effective. Current clinical trials are exploring fisetin's full potential at this optimized dose.*\u003csup\u003e1,3,9\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003eA standout feature of senolytic compounds like fisetin is their unique dosing strategy. Studies show that high doses taken over short periods are the most effective method for clearing senescent cells. This \"pulsed dosing\" or “hit-and-run” approach is the gold standard in research, supporting the removal of dysfunctional cells and supporting overall cellular health.*\u003csup\u003e1\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eIntroducing: The 5-Day Cellular Reset*1\u003c\/strong\u003e\u003cbr\u003eTo harness fisetin’s powerful senolytic benefits, we’ve designed the ProHealth 5-Day Cellular Reset protocol aimed at optimizing its role in supporting healthy aging:\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTake six (6) capsules of Pure Fisetin daily for 5 consecutive days.\u003c\/li\u003e\n\u003cli\u003eDiscontinue use on day 6.\u003c\/li\u003e\n\u003cli\u003eWait 4 weeks before repeating the cycle.  \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis strategic \"hit-and-run\" approach supports the body’s natural ability to clear out senescent cells. The protocol can be followed monthly or less frequently, depending on individual needs.*\u003csup\u003e1-5,9\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003e\u003cem\u003eNote: If this protocol feels too intensive, you can opt for one capsule of ProHealth Pure Fisetin daily for ongoing support.\u003c\/em\u003e*\u003csup\u003e6\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe Ultimate Weapon Against Zombie Cells*\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePotent Senolytic Action*1-5\u003csup\u003e*1-5\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eThe term \"senolytic\" comes from the Latin words senex (old) and lytic (destroying). Senolytics are compounds that help the body clear senescent cells—cells that have stopped dividing and contribute to aging. The buildup of these dysfunctional cells is a key hallmark of aging known as cellular senescence, which drives inflammation, impairs tissue function, and reduces the body's ability to regenerate. By promoting the removal of senescent cells, senolytic compounds like fisetin support cellular health and help counteract age-related decline.*\u003csup\u003e1-5,10\u003c\/sup\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003eClear Out \"Zombie\" Senescent Cells* \u003csup\u003e*1-5,9\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eSenolytics, including fisetin, selectively target senescent cells while leaving healthy cells unharmed. They work by disrupting Senescent Cell Anti-Apoptotic Pathways (SCAPs), which triggers apoptosis—the body’s natural process for removing damaged, dysfunctional cells. This process paves the way for healthier, more vibrant cells to thrive.*\u003csup\u003e1-5\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eActivate Autophagy*5,7*\u003c\/strong\u003e\u003cbr\u003eFisetin activates autophagy, the body’s built-in recycling process that removes damaged cell components and supports cellular renewal. By enhancing this natural repair mechanism, fisetin helps maintain healthy cell function and promote healthy aging.*\u003csup\u003e5,7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003eBoost SIRT1 Activity*8,11\u003c\/strong\u003e\u003cbr\u003eFisetin activates the SIRT1 “longevity gene,” boosting cellular repair, function, and resilience to help cells operate at their peak, just like in youth. While fasting and calorie restriction naturally stimulate SIRT1, fisetin can act as a potent “fasting mimetic,” increasing SIRT1 activity without the need for caloric restriction.*\u003csup\u003e8,11\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003eFood Alone Isn’t Enough\u003c\/strong\u003e\u003cbr\u003eFisetin is naturally present in foods like strawberries, apples, grapes, and cucumbers. However, the average diet provides only about 0.4 mg of fisetin per day—far below the senolytic threshold. To reach an effective dose through food alone, you’d need to consume an impractical amount of fruits and vegetables. That's why concentrated fisetin supplements are the most efficient way to achieve optimal benefits.*\u003csup\u003e12\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003ePure Fisetin is a Breakthrough in Senolytic Science*\u003cbr\u003e\u003c\/strong\u003eExperience the groundbreaking benefits of fisetin with ProHealth Pure Fisetin. At the leading edge of longevity science, fisetin is one ingredient that can have profoundly positive impacts on the aging process, by helping to address aging at the cellular level.*\u003csup\u003e1-5,7,9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003eOrder now and join the 200,000+ people who trust ProHealth Pure Fisetin for their cellular health!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIngredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFisetin:\u003c\/strong\u003e A potent polyphenol compound that helps the body clear senescent cells.*\u003csup\u003e1-5,9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e","brand":"ProHealth","offers":[{"title":"Default Title","offer_id":54297243779355,"sku":"PH709","price":55.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0966\/4485\/8139\/files\/PH709_FRNT_175CC_600x600-Rev1124_2x_6a65d74b-c205-4748-bbc7-ea7164a92863.webp?v=1792412585","url":"https:\/\/shop.hasanmirzamd.com\/products\/prohealth-pure-fisetin-250-mg-60-capsules","provider":"Hasan Mirza, MD","version":"1.0","type":"link"}