Pure Encapsulations Folate 5,000 Plus

High-Potency Methylation & Cardiovascular Support

Pure Encapsulations Folate 5,000 Plus is a professional-grade B-vitamin complex designed for individuals requiring significant folate support. This formula features Metafolin® L-5-MTHF, the universally metabolized and biologically active form of folate, combined with activated Vitamins B12 and B6. Together, these nutrients support the body's natural methylation processes, which are critical for genetic expression, cellular energy, and neurotransmitter production.

This targeted formula is particularly beneficial for those with genetic variations (such as MTHFR) that affect the metabolism of standard folic acid. By providing folate in its 5-MTHF form, the body bypasses several enzymatic steps, making the nutrient directly bioavailable. This helps maintain healthy homocysteine levels for cardiovascular wellness and supports overall neurological and psychological health.

Key Benefits

• Direct Bioavailability: Provides 5,000 mcg of Metafolin® L-5-MTHF, which is directly usable by the body without metabolic activation.

• Methylation Support: Essential for DNA synthesis, hormone production, and healthy cellular function throughout the body.

• Cardiovascular & Nerve Health: Promotes healthy endothelial function and supports nerve comfort and density.

• Cognitive & Emotional Wellness: Associated with supporting a positive mood and healthy neurotransmitter signaling.

Key Ingredients (per 1-capsule serving)

• Folate (as Metafolin®, L-5-MTHF): 5,000 mcg (8,333 mcg DFE)

• Vitamin B12 (as methylcobalamin): 1,000 mcg

• Vitamin B6 (as pyridoxal 5' phosphate): 25 mg

Suggested Use

Take 1 capsule daily, with a meal, or as directed by a healthcare professional.